2hzy | pdb_00002hzy

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Template:STRUCTURE 2hzy

File:2hzy.png

Mouse fumarylacetoacetate hydrolase complexes with a transition-state mimic of the complete substrate

Template:ABSTRACT PUBMED 17064256

About this Structure

2hzy is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Bateman RL, Ashworth J, Witte JF, Baker LJ, Bhanumoorthy P, Timm DE, Hurley TD, Grompe M, McClard RW. Slow-onset inhibition of fumarylacetoacetate hydrolase by phosphinate mimics of the tetrahedral intermediate: kinetics, crystal structure and pharmacokinetics. Biochem J. 2007 Mar 1;402(2):251-60. PMID:17064256 doi:10.1042/BJ20060961

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