2tct | pdb_00002tct

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File:2tct.png

Template:STRUCTURE 2tct

THE COMPLEX FORMED BETWEEN TET REPRESSOR AND TETRACYCLINE-MG2+ REVEALS MECHANISM OF ANTIBIOTIC RESISTANCE

Template:ABSTRACT PUBMED 7707374

About this Structure

2tct is a 1 chain structure with sequence from Escherichia coli. This structure supersedes the now removed PDB entry 1tct. Full crystallographic information is available from OCA.

Reference

  1. Kisker C, Hinrichs W, Tovar K, Hillen W, Saenger W. The complex formed between Tet repressor and tetracycline-Mg2+ reveals mechanism of antibiotic resistance. J Mol Biol. 1995 Mar 24;247(2):260-80. PMID:7707374
  2. Orth P, Schnappinger D, Sum PE, Ellestad GA, Hillen W, Saenger W, Hinrichs W. Crystal structure of the tet repressor in complex with a novel tetracycline, 9-(N,N-dimethylglycylamido)- 6-demethyl-6-deoxy-tetracycline. J Mol Biol. 1999 Jan 15;285(2):455-61. PMID:9878420 doi:10.1006/jmbi.1998.2290

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