2r43 | pdb_00002r43

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File:2r43.png

Template:STRUCTURE 2r43

I50V HIV-1 protease in complex with an amino decorated pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18692068

About this Structure

2r43 is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Bottcher J, Blum A, Heine A, Diederich WE, Klebe G. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease. J Mol Biol. 2008 Nov 7;383(2):347-57. Epub 2008 Jul 29. PMID:18692068 doi:10.1016/j.jmb.2008.07.062

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