2zpx | pdb_00002zpx

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Template:STRUCTURE 2zpx

File:2zpx.png

TNF Receptor Subtype One-selective TNF Mutant with Antagonistic Activity; R1antTNF-T8

Template:ABSTRACT PUBMED 19386778

About this Structure

2zpx is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Mukai Y, Nakamura T, Yoshioka Y, Shibata H, Abe Y, Nomura T, Taniai M, Ohta T, Nakagawa S, Tsunoda S, Kamada H, Yamagata Y, Tsutsumi Y. Fast binding kinetics and conserved 3D structure underlie the antagonistic activity of mutant TNF: useful information for designing artificial proteo-antagonists. J Biochem. 2009 Aug;146(2):167-72. Epub 2009 Apr 22. PMID:19386778 doi:10.1093/jb/mvp065

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OCA

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