3bi6 | pdb_00003bi6

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File:3bi6.png

Template:STRUCTURE 3bi6

Wee1 kinase complex with inhibitor PD352396

Template:ABSTRACT PUBMED 18191399

About this Structure

3bi6 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Smaill JB, Lee HH, Palmer BD, Thompson AM, Squire CJ, Baker EN, Booth RJ, Kraker A, Hook K, Denny WA. Synthesis and structure-activity relationships of soluble 8-substituted 4-(2-chlorophenyl)-9-hydroxypyrrolo[3,4-c]carbazole-1,3(2H,6H)-diones as inhibitors of the Wee1 and Chk1 checkpoint kinases. Bioorg Med Chem Lett. 2008 Feb 1;18(3):929-33. Epub 2008 Jan 11. PMID:18191399 doi:10.1016/j.bmcl.2007.12.046

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