2r3t | pdb_00002r3t

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Template:STRUCTURE 2r3t

File:2r3t.png

I50V HIV-1 protease mutant in complex with a carbamoyl decorated pyrrolidine-based inhibitor

Template:ABSTRACT PUBMED 18692068

About this Structure

2r3t is a 2 chain structure with sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  1. Bottcher J, Blum A, Heine A, Diederich WE, Klebe G. Structural and kinetic analysis of pyrrolidine-based inhibitors of the drug-resistant Ile84Val mutant of HIV-1 protease. J Mol Biol. 2008 Nov 7;383(2):347-57. Epub 2008 Jul 29. PMID:18692068 doi:10.1016/j.jmb.2008.07.062

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