2cl5 | pdb_00002cl5
From Proteopedia
CATECHOL-O-METHYLTRANSFERASE IN COMPLEX WITH AN INHIBITOR
About this Structure
2cl5 is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
Reference
- Palma PN, Rodrigues ML, Archer M, Bonifacio MJ, Loureiro AI, Learmonth DA, Carrondo MA, Soares-da-Silva P. Comparative study of ortho- and meta-nitrated inhibitors of catechol-O-methyltransferase: interactions with the active site and regioselectivity of O-methylation. Mol Pharmacol. 2006 Jul;70(1):143-53. Epub 2006 Apr 17. PMID:16618795 doi:10.1124/mol.106.023119
- Rodrigues ML, Bonifacio MJ, Soares-da-Silva P, Carrondo MA, Archer M. Crystallization and preliminary X-ray diffraction studies of a catechol-O-methyltransferase/inhibitor complex. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 Jan 1;61(Pt, 1):118-20. Epub 2004 Dec 24. PMID:16508109 doi:10.1107/S1744309104031197
- Frey D, Braun O, Briand C, Vasak M, Grutter MG. Structure of the mammalian NOS regulator dimethylarginine dimethylaminohydrolase: A basis for the design of specific inhibitors. Structure. 2006 May;14(5):901-11. PMID:16698551 doi:https://dx.doi.org/10.1016/j.str.2006.03.006
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Catechol O-methyltransferase
- Rattus norvegicus
- Archer, M.
- Bonifacio, M J.
- Carrondo, M A.
- Learmonth, D A.
- Loureiro, A I.
- Palma, P N.
- Rodrigues, M L.
- Soares-Da-Silva, P.
- Alternative initiation
- Catechol-o-methyltransferase
- Catecholamine metabolism
- Comt inhibitor
- Magnesium
- Membrane
- Metal-binding
- Methyltransferase
- Neurotransmitter degradation
- Phosphorylation
- Signal-anchor
- Transferase
- Transmembrane
