2etz | pdb_00002etz

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Template:STRUCTURE 2etz

File:2etz.png

The NMR minimized average structure of the Itk SH2 domain bound to a phosphopeptide

Template:ABSTRACT PUBMED 16436281

About this Structure

2etz is a 2 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.

Reference

  1. Pletneva EV, Sundd M, Fulton DB, Andreotti AH. Molecular details of Itk activation by prolyl isomerization and phospholigand binding: the NMR structure of the Itk SH2 domain bound to a phosphopeptide. J Mol Biol. 2006 Mar 24;357(2):550-61. Epub 2006 Jan 18. PMID:16436281 doi:https://dx.doi.org/10.1016/j.jmb.2005.12.073
  2. Mallis RJ, Brazin KN, Fulton DB, Andreotti AH. Structural characterization of a proline-driven conformational switch within the Itk SH2 domain. Nat Struct Biol. 2002 Dec;9(12):900-5. PMID:12402030 doi:https://dx.doi.org/10.1038/nsb864

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