2kqh | pdb_00002kqh

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File:2kqh.png

Template:STRUCTURE 2kqh

A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics

Template:ABSTRACT PUBMED 19705869

About this Structure

2kqh is a 1 chain structure. This structure supersedes the now removed PDB entry 2kj2. Full experimental information is available from OCA.

Reference

  1. Hsu ST, Varnai P, Bugaut A, Reszka AP, Neidle S, Balasubramanian S. A G-rich sequence within the c-kit oncogene promoter forms a parallel G-quadruplex having asymmetric G-tetrad dynamics. J Am Chem Soc. 2009 Sep 23;131(37):13399-409. PMID:19705869 doi:10.1021/ja904007p
  2. Fernando H, Reszka AP, Huppert J, Ladame S, Rankin S, Venkitaraman AR, Neidle S, Balasubramanian S. A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene. Biochemistry. 2006 Jun 27;45(25):7854-60. PMID:16784237 doi:10.1021/bi0601510

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