4iw5 | pdb_00004iw5

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Template:STRUCTURE 4iw5

File:4iw5.jpg

Thymidylate synthase ternary complex with dUMP and CB3717

Template:ABSTRACT PUBMED 16768437

About this Structure

4iw5 is a 2 chain structure with sequence from Escherichia coli k-12. This structure supersedes the now removed PDB entry 2g8o. Full crystallographic information is available from OCA.

Reference

  1. Newby Z, Lee TT, Morse RJ, Liu Y, Liu L, Venkatraman P, Santi DV, Finer-Moore JS, Stroud RM. The role of protein dynamics in thymidylate synthase catalysis: variants of conserved 2'-deoxyuridine 5'-monophosphate (dUMP)-binding Tyr-261. Biochemistry. 2006 Jun 20;45(24):7415-28. PMID:16768437 doi:10.1021/bi060152s

Proteopedia Page Contributors and Editors (what is this?)

OCA, Jaime Prilusky

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