3ge7 | pdb_00003ge7

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File:3ge7.png

Template:STRUCTURE 3ge7

tRNA-guanine transglycosylase in complex with 6-amino-4-{2-[(cyclopentylmethyl)amino]ethyl}-2-(methylamino)-1,7-dihydro-8H-imidazo[4,5-g]quinazolin-8-one

Template:ABSTRACT PUBMED 19894214

About this Structure

3ge7 is a 1 chain structure with sequence from Zymomonas mobilis. Full crystallographic information is available from OCA.

Reference

  1. Ritschel T, Kohler PC, Neudert G, Heine A, Diederich F, Klebe G. How to Replace the Residual Solvation Shell of Polar Active Site Residues to Achieve Nanomolar Inhibition of tRNA-Guanine Transglycosylase. ChemMedChem. 2009 Dec;4(12):2012-23. PMID:19894214 doi:10.1002/cmdc.200900343

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OCA

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