3ggs | pdb_00003ggs

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Template:STRUCTURE 3ggs

File:3ggs.png

Human purine nucleoside phosphorylase double mutant E201Q,N243D complexed with 2-fluoro-2'-deoxyadenosine

Template:ABSTRACT PUBMED 19388075

About this Structure

3ggs is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Afshar S, Sawaya MR, Morrison SL. Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. Protein Sci. 2009 May;18(5):1107-14. PMID:19388075 doi:10.1002/pro.91

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