2xyn | pdb_00002xyn

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File:2xyn.png

Template:STRUCTURE 2xyn

HUMAN ABL2 IN COMPLEX WITH AURORA KINASE INHIBITOR VX-680

Template:ABSTRACT PUBMED 21417343

About this Structure

2xyn is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3nsv. Full crystallographic information is available from OCA.

Reference

  1. Salah E, Ugochukwu E, Barr AJ, von Delft F, Knapp S, Elkins JM. Crystal Structures of ABL-Related Gene (ABL2) in Complex with Imatinib, Tozasertib (VX-680), and a Type I Inhibitor of the Triazole Carbothioamide Class. J Med Chem. 2011 Mar 18. PMID:21417343 doi:10.1021/jm101506n

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