3ekk | pdb_00003ekk
From Proteopedia
Insulin receptor kinase complexed with an inhibitor
About this Structure
3ekk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Chamberlain SD, Wilson JW, Deanda F, Patnaik S, Redman AM, Yang B, Shewchuk L, Sabbatini P, Leesnitzer MA, Groy A, Atkins C, Gerding R, Hassell AM, Lei H, Mook RA Jr, Moorthy G, Rowand JL, Stevens KL, Kumar R, Shotwell JB. Discovery of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidines: Potent inhibitors of the IGF-1R receptor tyrosine kinase. Bioorg Med Chem Lett. 2008 Nov 18. PMID:19056263 doi:S0960-894X(08)01424-8
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Receptor protein-tyrosine kinase
- Atkins, C.
- Chamberlain, S.
- Deanda, F.
- Dumble, M.
- Gerding, R.
- Groy, A.
- Korenchuk, S.
- Kumar, R.
- Lei, H.
- Mook, R.
- Moorthy, G.
- Redman, A.
- Rowland, J.
- Sabbatini, P.
- Shewchuk, L.
- Atp-binding
- Carbohydrate metabolism
- Cleavage on pair of basic residue
- Diabetes mellitus
- Disease mutation
- Glycoprotein
- Insulin
- Kinase
- Membrane
- Nucleotide-binding
- Phosphoprotein
- Receptor
- Transferase
- Transmembrane
- Tyrosine kinase
- Tyrosine-protein kinase
