3pp7 | pdb_00003pp7

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Template:STRUCTURE 3pp7

Crystal structure of Leishmania mexicana pyruvate kinase in complex with the drug suramin, an inhibitor of glycolysis.

Template:ABSTRACT PUBMED 21733839

About this Structure

3pp7 is a 2 chain structure with sequence from Leishmania mexicana. Full crystallographic information is available from OCA.

See Also

Reference

  1. Morgan HP, McNae IW, Nowicki MW, Zhong W, Michels PA, Auld DS, Fothergill-Gilmore LA, Walkinshaw MD. The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site. J Biol Chem. 2011 Jul 5. PMID:21733839 doi:10.1074/jbc.M110.212613

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