3ii5 | pdb_00003ii5
From Proteopedia
The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor
About this Structure
3ii5 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Berger DM, Torres N, Dutia M, Powell D, Ciszewski G, Gopalsamy A, Levin JI, Kim KH, Xu W, Wilhelm J, Hu Y, Collins K, Feldberg L, Kim S, Frommer E, Wojciechowicz D, Mallon R. Non-hinge-binding pyrazolo[1,5-a]pyrimidines as potent B-Raf kinase inhibitors. Bioorg Med Chem Lett. 2009 Dec 1;19(23):6519-23. Epub 2009 Oct 26. PMID:19864136 doi:10.1016/j.bmcl.2009.10.049
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Non-specific serine/threonine protein kinase
- Breger, D.
- Ciszewski, G.
- Dutia, M.
- Powell, D.
- Torres, N.
- Xu, W.
- Atp-binding
- B-raf
- Cardiomyopathy
- Disease mutation
- Kinase
- Metal-binding
- Nucleotide-binding
- Phorbol-ester binding
- Phosphoprotein
- Protein-inhibitor complex
- Proto-oncogene
- Serine/threonine-protein kinase
- Transferase
- Zinc-finger
