1cjc | pdb_00001cjc
From Proteopedia
STRUCTURE OF ADRENODOXIN REDUCTASE OF MITOCHONDRIAL P450 SYSTEMS
Template:ABSTRACT PUBMED 10369776
Function
[ADRO_BOVIN] Serves as the first electron transfer protein in all the mitochondrial P450 systems. Including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver.
About this Structure
1cjc is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
See Also
Reference
- Ziegler GA, Vonrhein C, Hanukoglu I, Schulz GE. The structure of adrenodoxin reductase of mitochondrial P450 systems: electron transfer for steroid biosynthesis. J Mol Biol. 1999 Jun 18;289(4):981-90. PMID:10369776 doi:10.1006/jmbi.1999.2807
- Ojha S, Meng EC, Babbitt PC. Evolution of function in the "two dinucleotide binding domains" flavoproteins. PLoS Comput Biol. 2007 Jul;3(7):e121. PMID:17658942 doi:10.1371/journal.pcbi.0030121
