2g76 | pdb_00002g76
From Proteopedia
Crystal structure of human 3-phosphoglycerate dehydrogenase
Disease
[SERA_HUMAN] Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency) [MIM:601815]. It is characterized by congenital microcephaly, psychomotor retardation, and seizures.
About this Structure
2g76 is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Phosphoglycerate dehydrogenase
- Arrowsmith, C.
- Delft, F von.
- Edwards, A.
- Gileadi, O.
- Oppermann, U.
- SGC, Structural Genomics Consortium.
- Salah, E.
- Savitsky, P.
- Sundstrom, M.
- Turnbull, A P.
- Weigelt, J.
- 2-hydroxyacid dehydrogenase
- Oxidoreductase
- Phosphoglycerate dehydrogenase deficiency
- Serine metabolism
- Sgc
- Structural genomic
- Structural genomics consortium
