1ayr | pdb_00001ayr
From Proteopedia
ARRESTIN FROM BOVINE ROD OUTER SEGMENTS
Disease
[ARRS_BOVIN] Note=S-antigen induces autoimmune uveitis.
Function
[ARRS_BOVIN] Arrestin is one of the major proteins of the ros (retinal rod outer segments); it binds to photoactivated-phosphorylated rhodopsin, thereby apparently preventing the transducin-mediated activation of phosphodiesterase. Isoform B plays a role in the phototransduction cascade.
About this Structure
1ayr is a 4 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
- Granzin J, Wilden U, Choe HW, Labahn J, Krafft B, Buldt G. X-ray crystal structure of arrestin from bovine rod outer segments. Nature. 1998 Feb 26;391(6670):918-21. PMID:9495348 doi:10.1038/36147
