3h2v | pdb_00003h2v
From Proteopedia
Human raver1 RRM1 domain in complex with human vinculin tail domain Vt
Function
[RAVR1_HUMAN] Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA (By similarity).
About this Structure
3h2v is a 8 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Lee JH, Rangarajan ES, Yogesha SD, Izard T. Raver1 interactions with vinculin and RNA suggest a feed-forward pathway in directing mRNA to focal adhesions. Structure. 2009 Jun 10;17(6):833-42. PMID:19523901 doi:S0969-2126(09)00193-2
