2lx7 | pdb_00002lx7

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Template:STRUCTURE 2lx7

Solution NMR structure of SH3 domain of growth arrest-specific protein 7 (GAS7) (fragment 1-60) from Homo sapiens, Northeast Structural Genomics Consortium (NESG) Target HR8574A

Disease

[GAS7_HUMAN] Note=A chromosomal aberration involving GAS7 is found in acute myeloid leukemia. Translocation t(11;17)(q23;p13) with MLL/HRX.

Function

[GAS7_HUMAN] May play a role in promoting maturation and morphological differentiation of cerebellar neurons.

About this Structure

2lx7 is a 1 chain structure with sequence from Homo sapiens. Full experimental information is available from OCA.

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