2deb | pdb_00002deb
Crystal structure of rat carnitine palmitoyltransferase 2 in space group C2221
|
Overview
Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.
About this Structure
2DEB is a Single protein structure of sequence from Rattus norvegicus with BOG, COA and PLM as ligands. Active as Carnitine O-palmitoyltransferase, with EC number 2.3.1.21 Full crystallographic information is available from OCA.
Reference
A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:16615901
Page seeded by OCA on Thu Feb 21 16:57:58 2008
