1n2s | pdb_00001n2s

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Template:STRUCTURE 1n2s

CRYSTAL STRUCTURE OF DTDP-6-DEOXY-L-LYXO-4-HEXULOSE REDUCTASE (RMLD) IN COMPLEX WITH NADH

Template:ABSTRACT PUBMED 12057193

Function

[RFBD_SALTY] Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. RmlD uses NADH and NADPH nearly equally well.

About this Structure

1n2s is a 1 chain structure with sequence from Salmonella enterica subsp. enterica serovar typhimurium. This structure supersedes the now removed PDB entry 1kc0. Full crystallographic information is available from OCA.

Reference

  1. Blankenfeldt W, Kerr ID, Giraud MF, McMiken HJ, Leonard G, Whitfield C, Messner P, Graninger M, Naismith JH. Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode. Structure. 2002 Jun;10(6):773-86. PMID:12057193

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