3iqe | pdb_00003iqe

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Template:STRUCTURE 3iqe

Structure of F420 dependent methylene-tetrahydromethanopterin dehydrogenase in complex with methylene-tetrahydromethanopterin and coenzyme F420

Template:ABSTRACT PUBMED 19761261

Function

[MTD_METKA] Catalyzes the reversible reduction of methenyl-H(4)MPT(+) to methylene-H(4)MPT.[1]

About this Structure

3iqe is a 6 chain structure with sequence from Methanopyrus kandleri. Full crystallographic information is available from OCA.

Reference

  1. Ceh K, Demmer U, Warkentin E, Moll J, Thauer RK, Shima S, Ermler U. Structural Basis of the Hydride Transfer Mechanism in F(420)-Dependent Methylenetetrahydromethanopterin Dehydrogenase. Biochemistry. 2009 Sep 29. PMID:19761261 doi:10.1021/bi901104d
  1. ↑ Klein AR, Thauer RK. Overexpression of the coenzyme-F420-dependent N5,N10-methylenetetrahydromethanopterin dehydrogenase gene from the hyperthermophilic Methanopyrus kandleri. Eur J Biochem. 1997 Apr 15;245(2):386-91. PMID:9151968

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