3jqa | pdb_00003jqa
From Proteopedia
Crystal structure of pteridine reductase 1 (PTR1) from Trypanosoma brucei in ternary complex with cofactor (NADP+) and inhibitor 2-amino-1,9-dihydro-6H-purine-6-thione (DX4)
Template:ABSTRACT PUBMED 19916554
About this Structure
3jqa is a 4 chain structure with sequence from Trypanosoma brucei. This structure supersedes the now removed PDB entry 3bmg. Full crystallographic information is available from OCA.
Reference
- Tulloch LB, Martini VP, Iulek J, Huggan JK, Lee JH, Gibson CL, Smith TK, Suckling CJ, Hunter WN. Structure-Based Design of Pteridine Reductase Inhibitors Targeting African Sleeping Sickness and the Leishmaniases. J Med Chem. 2009 Nov 16. PMID:19916554 doi:10.1021/jm901059x
