3it4 | pdb_00003it4
From Proteopedia
The Crystal Structure of Ornithine Acetyltransferase from Mycobacterium tuberculosis (Rv1653) at 1.7 A
Template:ABSTRACT PUBMED 20184895
Function
[ARGJ_MYCTU] Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity).[HAMAP-Rule:MF_01106]
About this Structure
3it4 is a 4 chain structure with sequence from Mycobacterium tuberculosis. Full crystallographic information is available from OCA.
Reference
- Sankaranarayanan R, Cherney MM, Garen C, Garen G, Niu C, Yuan M, James MN. The molecular structure of ornithine acetyltransferase from Mycobacterium tuberculosis bound to ornithine, a competitive inhibitor. J Mol Biol. 2010 Apr 9;397(4):979-90. Epub 2010 Feb 22. PMID:20184895 doi:10.1016/j.jmb.2010.02.018
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Glutamate N-acetyltransferase
- Mycobacterium tuberculosis
- Cherney, M M.
- Garen, C.
- Garen, G.
- James, M N.
- Sankaranarayanan, R.
- TBSGC, TB Structural Genomics Consortium.
- Yuan, M.
- Acyltransferase
- Amino-acid biosynthesis
- Arginine biosynthesis
- Multifunctional enzyme
- Ornithine acetyltransferase
- Structural genomic
- Transferase
