3iwu | pdb_00003iwu

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Template:STRUCTURE 3iwu

Crystal structure of Y116T/I16A double mutant of 5-hydroxyisourate hydrolase

Template:ABSTRACT PUBMED 16952372

Function

[HIUH_DANRE] Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU).

About this Structure

3iwu is a 8 chain structure with sequence from Danio rerio. Full crystallographic information is available from OCA.

Reference

  1. Zanotti G, Cendron L, Ramazzina I, Folli C, Percudani R, Berni R. Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter. J Mol Biol. 2006 Oct 13;363(1):1-9. Epub 2006 Aug 2. PMID:16952372 doi:10.1016/j.jmb.2006.07.079

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