3it5 | pdb_00003it5

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Template:STRUCTURE 3it5

Crystal Structure of the LasA Virulence Factor from Pseudomonas aeruginosa

Template:ABSTRACT PUBMED 20026068

Function

[LASA_PSEAE] Involved in proteolysis and elastolysis. Degradation of elastin is likely to contribute to the pathogenicity of P.aeruginosa.

About this Structure

3it5 is a 4 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.

Reference

  1. Spencer J, Murphy LM, Conners R, Sessions RB, Gamblin SJ. Crystal structure of the LasA virulence factor from Pseudomonas aeruginosa: substrate specificity and mechanism of M23 metallopeptidases. J Mol Biol. 2010 Mar 5;396(4):908-23. Epub 2009 Dec 21. PMID:20026068 doi:10.1016/j.jmb.2009.12.021

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