3irc | pdb_00003irc

Function

[Q9J7C6_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS026470_004_099774]

About this Structure

3irc is a 1 chain structure with sequence from Dengue virus 1. This structure supersedes the now removed PDB entry 3egp. Full crystallographic information is available from OCA.

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