3hbx | pdb_00003hbx

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Template:STRUCTURE 3hbx

Crystal structure of GAD1 from Arabidopsis thaliana

Template:ABSTRACT PUBMED 19580813

Function

[DCE1_ARATH] Catalyzes the production of GABA. The calmodulin-binding is calcium-dependent and it is proposed that this may, directly or indirectly, form a calcium regulated control of GABA biosynthesis.[1]

About this Structure

3hbx is a 6 chain structure with sequence from Arabidopsis thaliana. Full crystallographic information is available from OCA.

Reference

  1. Gut H, Dominici P, Pilati S, Astegno A, Petoukhov MV, Svergun DI, Grutter MG, Capitani G. A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase. J Mol Biol. 2009 Sep 18;392(2):334-51. Epub 2009 Jul 4. PMID:19580813 doi:10.1016/j.jmb.2009.06.080
  1. ↑ Zik M, Arazi T, Snedden WA, Fromm H. Two isoforms of glutamate decarboxylase in Arabidopsis are regulated by calcium/calmodulin and differ in organ distribution. Plant Mol Biol. 1998 Aug;37(6):967-75. PMID:9700069

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