CD47

File:2jjs.png

Crystal structure of hCD47 residues 19-136 (mutant) complex with SIRP α 2jjs

CD47 (Cluster of Differentiation 47) is a protein which is expressed by cancer cells to avoid detection by the immune system. Antobodies against CD47 were found to bring effective cure against cancer in mice in a variety of cancers tested.

3D Structures of CD47

Updated on 03-April-2013

2jjs, 2jjt – hCD47 residues 19-136 (mutant) + SIRP α
2vsc – hCD47 residues 19-136 (mutant)

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Michal Harel, Alexander Berchansky, Joel L. Sussman