3owg | pdb_00003owg

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Template:STRUCTURE 3owg

Crystal structure of vaccinia virus Polyadenylate polymerase(vp55)

Template:ABSTRACT PUBMED 23519670

Function

[PAP1_VACCW] Polymerase that creates the 3'-poly(A) tail of mRNA's.

About this Structure

3owg is a 2 chain structure with sequence from Vaccinia virus wr. Full crystallographic information is available from OCA.

Reference

  1. Moure CM, Bowman BR, Gershon PD, Quiocho FA. Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol Cell. 2006 May 5;22(3):339-49. PMID:16678106 doi:10.1016/j.molcel.2006.03.015
  2. Li C, Li H, Zhou S, Sun E, Yoshizawa J, Poulos TL, Gershon PD. Polymerase translocation with respect to single-stranded nucleic acid: looping or wrapping of primer around a poly(A) polymerase. Structure. 2009 May 13;17(5):680-9. PMID:19446524 doi:10.1016/j.str.2009.03.012

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