4ib4 | pdb_00004ib4
From Proteopedia
Crystal structure of the chimeric protein of 5-HT2B-BRIL in complex with ergotamine
Function
[5HT2B_HUMAN] This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Plays a role in the regulation of impulsive behavior.
About this Structure
4ib4 is a 1 chain structure. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Cherezov, V.
- Chu, M.
- GPCR, GPCR Network.
- Han, G W.
- Huang, X.
- Jiang, Y.
- Katritch, V.
- Liu, W.
- McCorvy, J D.
- Roth, B L.
- Siu, F Y.
- Stevens, R C.
- Vardy, E.
- Wacker, D.
- Wang, C.
- Xu, H E.
- Electron transport
- Ergotamine
- Gpcr
- Gpcr dock
- Gpcr network
- Membrane protein
- Novel protein engineering
- Psi-biology
- Signaling protein
- Structural genomic
