3ke1 | pdb_00003ke1
From Proteopedia
Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei in complex with a fragment-nucleoside fusion D000161829
Function
[ISPF_BURPS] Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity).[HAMAP-Rule:MF_00107]
About this Structure
3ke1 is a 3 chain structure with sequence from Burkholderia pseudomallei. Full crystallographic information is available from OCA.
See Also
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
- Burkholderia pseudomallei
- SSGCID, Seattle Structural Genomics Center for Infectious Disease.
- D000161829
- Fbdd
- Fragment crystallography
- Fragment-based drug-design
- Isoprene biosynthesis
- Lyase
- Metal-binding
- Niaid
- Nucleoside analog
- Seattle structural genomics center for infectious disease
- Ssgcid
