3kos | pdb_00003kos

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Template:STRUCTURE 3kos

Structure of the AmpR effector binding domain from Citrobacter freundii

Template:ABSTRACT PUBMED 20594961

Function

[AMPR_CITFR] Regulates the expression of the beta-lactamase gene. Represses cephalosporinase (AmpC) in the presence of beta-lactams and induces it in the absence of them.

About this Structure

3kos is a 1 chain structure with sequence from Citrobacter freundii. Full crystallographic information is available from OCA.

Reference

  1. Balcewich MD, Reeve TM, Orlikow EA, Donald LJ, Vocadlo DJ, Mark BL. Crystal structure of the AmpR effector binding domain provides insight into the molecular regulation of inducible ampc beta-lactamase. J Mol Biol. 2010 Jul 30;400(5):998-1010. Epub 2010 May 31. PMID:20594961 doi:10.1016/j.jmb.2010.05.040

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