3kup | pdb_00003kup
From Proteopedia
Crystal Structure of the CBX3 Chromo Shadow Domain
Function
[CBX3_HUMAN] Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
About this Structure
3kup is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Homo sapiens
- Arrowsmith, C H.
- Bochkarev, A.
- Bountra, C.
- Edwards, A M.
- Kozieradzki, I.
- Li, Y.
- Li, Z.
- Min, J.
- Ouyang, H.
- SGC, Structural Genomics Consortium.
- Tempel, W.
- Weigelt, J.
- Chromatin regulator
- Chromo shadow domain
- Nucleus
- Phosphoprotein
- Repressor
- Sgc
- Structural genomics consortium
- Transcription
- Transcription regulation
