3lha | pdb_00003lha

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Template:STRUCTURE 3lha

Crystal structure of mouse VPS26B(R240S/G241A/E242S) in spacegroup P41 21 2

Template:ABSTRACT PUBMED 20875039

Function

[VP26B_MOUSE] Probable component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network.

About this Structure

3lha is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Norwood SJ, Shaw DJ, Cowieson NP, Owen DJ, Teasdale RD, Collins BM. Assembly and solution structure of the core retromer protein complex. Traffic. 2010 Sep 28. doi: 10.1111/j.1600-0854.2010.01124.x. PMID:20875039 doi:10.1111/j.1600-0854.2010.01124.x

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