3mex | pdb_00003mex
From Proteopedia
Crystal structure of MexR in oxidized state
Function
[MEXR_PSEAE] Repressor of the mexAB-oprM multidrug resistance operon. Also represses its own expression. Many variants lead to increased expression of the mexAB-oprM operon.
About this Structure
3mex is a 2 chain structure with sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
Reference
- Chen H, Yi C, Zhang J, Zhang W, Ge Z, Yang CG, He C. Structural insight into the oxidation-sensing mechanism of the antibiotic resistance of regulator MexR. EMBO Rep. 2010 Sep;11(9):685-90. Epub 2010 Jul 9. PMID:20616806 doi:10.1038/embor.2010.96
