3lpf | pdb_00003lpf

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Template:STRUCTURE 3lpf

Structure of E. coli beta-Glucuronidase bound with a novel, potent inhibitor 1-((6,7-dimethyl-2-oxo-1,2-dihydroquinolin-3-yl)methyl)-1-(2-hydroxyethyl)-3-(3-methoxyphenyl)thiourea

Template:ABSTRACT PUBMED 21051639

About this Structure

3lpf is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Wallace BD, Wang H, Lane KT, Scott JE, Orans J, Koo JS, Venkatesh M, Jobin C, Yeh LA, Mani S, Redinbo MR. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science. 2010 Nov 5;330(6005):831-5. PMID:21051639 doi:10.1126/science.1191175

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