3ly8 | pdb_00003ly8

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Template:STRUCTURE 3ly8

Crystal structure of mutant D471E of the periplasmic domain of CadC

Template:ABSTRACT PUBMED 21308846

Function

[CADC_ECOLI] Required for Pcad induction, a promoter upstream of cadBA that is responsible for the pH-regulated expression of CadA and CadB. Probably acts as an activating transcription factor.[1]

About this Structure

3ly8 is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

  1. Eichinger A, Haneburger I, Koller C, Jung K, Skerra A. Crystal structure of the sensory domain of Escherichia coli CadC, a member of the ToxR-like protein family. Protein Sci. 2011 Jan 24. doi: 10.1002/pro.594. PMID:21308846 doi:10.1002/pro.594
  1. ↑ Watson N, Dunyak DS, Rosey EL, Slonczewski JL, Olson ER. Identification of elements involved in transcriptional regulation of the Escherichia coli cad operon by external pH. J Bacteriol. 1992 Jan;174(2):530-40. PMID:1370290

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