3lyr | pdb_00003lyr

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Template:STRUCTURE 3lyr

Human Early B-cell Factor 1 (EBF1) DNA-binding domain

Template:ABSTRACT PUBMED 20592035

Function

[COE1_HUMAN] Transcriptional activator which recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity).

About this Structure

3lyr is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. Siponen MI, Wisniewska M, Lehtio L, Johansson I, Svensson L, Raszewski G, Nilsson L, Sigvardsson M, Berglund H. Structural determination of functional domains in early B-cell factor (EBF) family of transcription factors reveals similarities to Rel DNA-binding proteins and a novel dimerization motif. J Biol Chem. 2010 Aug 20;285(34):25875-9. Epub 2010 Jun 30. PMID:20592035 doi:10.1074/jbc.C110.150482

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