3lvl | pdb_00003lvl
From Proteopedia
Crystal Structure of E.coli IscS-IscU complex
Function
[ISCS_ECO57] Catalyzes the removal of elemental sulfur and selenium atoms from cysteine and selenocysteine to produce alanine. Functions as a sulfur delivery protein for NAD, biotin and Fe-S cluster synthesis. Transfers sulfur on 'Cys-456' of ThiI in a transpersulfidation reaction. Functions also as a selenium delivery protein in the pathway for the biosynthesis of selenophosphate (By similarity).
About this Structure
3lvl is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Shi R, Proteau A, Villarroya M, Moukadiri I, Zhang L, Trempe JF, Matte A, Armengod ME, Cygler M. Structural basis for Fe-S cluster assembly and tRNA thiolation mediated by IscS protein-protein interactions. PLoS Biol. 2010 Apr 13;8(4):e1000354. PMID:20404999 doi:10.1371/journal.pbio.1000354
