3m2v | pdb_00003m2v

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Template:STRUCTURE 3m2v

Structural Insight into Methyl-Coenzyme M Reductase Chemistry using Coenzyme B Analogues

Template:ABSTRACT PUBMED 20707311

Function

[MCRA_METTM] Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide. [MCRG_METTM] Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide. [MCRB_METTM] Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide.

About this Structure

3m2v is a 6 chain structure with sequence from Methanothermobacter marburgensis. Full crystallographic information is available from OCA.

Reference

  1. Cedervall PE, Dey M, Pearson AR, Ragsdale SW, Wilmot CM. Structural insight into methyl-coenzyme M reductase chemistry using coenzyme B analogues . Biochemistry. 2010 Sep 7;49(35):7683-93. PMID:20707311 doi:10.1021/bi100458d

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