2vwi | pdb_00002vwi

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Template:STRUCTURE 2vwi

Structure of the OSR1 kinase, a hypertension drug target

Function

[OXSR1_HUMAN] Regulates downstream kinases in response to environmental stress. May also have a function in regulating the actin cytoskeleton.[1]

About this Structure

2vwi is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  1. ↑ Chen W, Yazicioglu M, Cobb MH. Characterization of OSR1, a member of the mammalian Ste20p/germinal center kinase subfamily. J Biol Chem. 2004 Mar 19;279(12):11129-36. Epub 2004 Jan 5. PMID:14707132 doi:10.1074/jbc.M313562200

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