3mul | pdb_00003mul

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Template:STRUCTURE 3mul

Crystal structure of Brd4 bromodomain 1 with butyrylated histone H3-K(buty)14

Function

[BRD4_MOUSE] Plays a role in a process governing chromosomal dynamics during mitosis.[1]

About this Structure

3mul is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  1. Vollmuth F, Geyer M. Interaction of propionylated and butyrylated histone H3 lysine marks with Brd4 bromodomains. Angew Chem Int Ed Engl. 2010 Sep 10;49(38):6768-72. PMID:20715035 doi:10.1002/anie.201002724
  1. ↑ Dey A, Ellenberg J, Farina A, Coleman AE, Maruyama T, Sciortino S, Lippincott-Schwartz J, Ozato K. A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition. Mol Cell Biol. 2000 Sep;20(17):6537-49. PMID:10938129

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