3moh | pdb_00003moh
From Proteopedia
The structure of rat cytosolic PEPCK mutant A467G in complex with phosphoglycolate and GDP
Template:ABSTRACT PUBMED 20476774
Function
[PCKGC_RAT] Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle.
About this Structure
3moh is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.
See Also
Reference
- Johnson TA, Holyoak T. Increasing the conformational entropy of the Omega-loop lid domain in PEPCK impairs catalysis and decreases catalytic fidelity. Biochemistry. 2010 May 17. PMID:20476774 doi:10.1021/bi100399e
