3nm5 | pdb_00003nm5

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Template:STRUCTURE 3nm5

Helicobacter pylori MTAN complexed with Formycin A

Template:ABSTRACT PUBMED 20954236

Function

[MTNN_HELPJ] Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) (By similarity).

About this Structure

3nm5 is a 2 chain structure with sequence from Helicobacter pylori. Full crystallographic information is available from OCA.

Reference

  1. Ronning DR, Iacopelli NM, Mishra V. Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. Protein Sci. 2010 Oct 15. PMID:20954236 doi:10.1002/pro.524

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OCA

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