3nil | pdb_00003nil

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Revision as of 12:04, 24 April 2013 by OCA (talk | contribs) (Protected "3nil" [edit=sysop:move=sysop])
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Template:STRUCTURE 3nil

The structure of UBR box (RDAA)

Template:ABSTRACT PUBMED 20835240

Function

[UBR1_YEAST] Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.

About this Structure

3nil is a 5 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

See Also

Reference

  1. Choi WS, Jeong BC, Joo YJ, Lee MR, Kim J, Eck MJ, Song HK. Structural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligases. Nat Struct Mol Biol. 2010 Sep 12. PMID:20835240 doi:10.1038/nsmb.1907

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