3p5p | pdb_00003p5p
From Proteopedia
Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate
Template:ABSTRACT PUBMED 21160477
Function
[TASY_TAXBR] Catalyzes the cyclization of the ubiquitous isoprenoid intermediate geranylgeranyl diphosphate to taxa-4,11-diene, the parent olefin with a taxane skeleton.
About this Structure
3p5p is a 1 chain structure with sequence from Taxus brevifolia. Full crystallographic information is available from OCA.
Reference
- Koksal M, Jin Y, Coates RM, Croteau R, Christianson DW. Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesis. Nature. 2010 Dec 15. PMID:21160477 doi:10.1038/nature09628
