3p76 | pdb_00003p76
From Proteopedia
X-ray crystal structure of Aquifex aeolicus LpxC complexed SCH1379777
Template:ABSTRACT PUBMED 21273067
Function
[LPXC_AQUAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).
About this Structure
3p76 is a 1 chain structure with sequence from Aquifex aeolicus. Full crystallographic information is available from OCA.
Reference
- Faruk Mansoor U, Vitharana D, Reddy PA, Daubaras DL, McNicholas P, Orth P, Black T, Arshad Siddiqui M. Design and synthesis of potent Gram-negative specific LpxC inhibitors. Bioorg Med Chem Lett. 2011 Feb 15;21(4):1155-61. Epub 2010 Dec 28. PMID:21273067 doi:10.1016/j.bmcl.2010.12.111
